ITGAM and Hyperglycemia: Although it cannot be classified as T1D or T2D, neonatal hyperglycemia (induced by injecting STZ on postnatal day 2 rats) increases the number of CD11b+ microglia in the hippocampal CA1 region at postnatal day 6 and triggers long-term deficits in learning and memory and decreased dendritic density in 3-month-old rats [265].