Notably, from the 21 genes tested, we identified higher expression of FOXO1 and PPARGC1B (Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 Beta, alternatively known as PGC-1β) as independent markers related with relapse-free survival (RFS) in breast cancer patients irrespective of breast cancer subtypes, including TNBC (Fig. 5a). The gene discussed is PPARGC1B; the disease is breast cancer.