NUDT1 and in situ carcinoma: In this context, our data provide a detailed metabolic analysis to assess how STS potentiate the cytotoxic effect of chemotherapeutic agents that causes DNA damage (DXR or CIS) or inhibit oxidative stress-induced DNA damage repair (MTH1 inhibitor) in TNBC cells, while protecting non transformed mammary cells in vitro (Fig. 1, Additional file 1: Fig. S1a, Additional file 2: Fig. S2).