Another random forest Model 2 based on the selected 2 clinical features (ALT and AFP levels) and 1 general imaging feature (presence or absence of portal vein thrombosis) resulted in an AUC of 0.867 with a 95% confidence interval (CI) of 0.765–0.968 for predicting treatment response after TACE. This evidence concerns the gene GPT and Portal vein thrombosis.