Anti-B7-H3 antibody reduced the burden of kidney tumors (Supplementary Fig. 3n, o), with the gross kidney tumor score decreased by 50% (p < 0.001) (Supplementary Fig. 3p) and the microscopic kidney tumor score reduced by 70% (p < 0.001) (Supplementary Fig. 3q). Here, CD276 is linked to kidney neoplasm.