WNT2 and neoplasm: These include well-characterized tumor stroma genes such as WNT2,40WISP1,63,64ITGB2,65WNT5A,45VCAM1,39,41 and ICAM1. 66 Moreover, by transcriptomic and proteomic approaches, as well as secretome analysis, we provide a list of differentially expressed molecules that are implicated in ECM organization as well as tumor and immune cell signaling.