Moreover, in 7-day co-cultures of CD1d+ tumor cell lines and type 1 NKT and/or Vγ9Vδ2-T cells, CD1d-Vδ2 bsTCE mediated antitumor activity at a low E:T ratio of 1:10, which was variably accompanied by expansion of type 1 NKT and/or Vγ9Vδ2-T cells (Figures 2D, 2E, S2D, and S2E). Here, CD1D is linked to neoplasm.