In gastric cancer (GC), different lncRNAs are related to drug resistance, by modulating the expression of drug resistance-related genes, such as the oncogenic lncRNAs MACC1-AS1, PVT1 and HAGLR, which are upregulated and promote 5-FU resistance in GC cells (Liu et al., 2022). Here, MACC1 is linked to gastric cancer.