Moreover, IL4I1 was found to play a critical role in the development of ovarian cancer (Zhao et al., 2021), head-neck cancer (Mazzoni et al., 2021), cutaneous melanoma (Prevost-Blondel and Richard, 2019), and ccRCC (Liu et al., 2020). The gene discussed is IL4I1; the disease is nonpapillary renal cell carcinoma.