Guan et al.47 reported that Tan IIA could induce the up-regulation of p53 protein expression in BGC-823 and NCI-H87 gastric cancer cells, while the p53 protein could bind to the promoter region of SLC7A11 and inhibit its transcription, thereby inducing ferroptosis and inhibiting the proliferation of gastric cancer cells. The gene discussed is TP53; the disease is gastric cancer.