For cancer treatment, there is evidence that artemisinin and its derivatives (such as artesunate, artemisinin, and dihydroartemisinin (DHA)) induce antioxidant stress in cancer cells by accumulating ROS, overexerting lipid peroxides and iron, and causing ferroptosis.44 DHA, a semisynthetic derivative of artemisinin, induces ferroptosis in leukemia cells and head and neck cancer cells.45 Recently, β-elemene was shown to be a ferroptosis inducer that sensitized KRAS-mutated colorectal cancer cells to the chemotherapeutic agent cetuximab.46 The gene discussed is KRAS; the disease is cancer.