Furthermore, the expression ofβ-catenin and c-myc in the Wnt/β-catenin signalling pathway was increased in the RBBP5 knockdown group in xenogeneic tumor tissues of nude mice, and N-cadherin and MMP-7 in EMT also increased (Figure 7(d), Supplementary Figure S1). This evidence concerns the gene RBBP5 and neoplasm.