IL4 and Pleural effusion: Besides, in our previous pharmacological experiment, compared with NC group, a significantly increased lung wet/dry weight ratio, lung indices, lung water content, pleural effusion accumulation, amount of leukocyte extravasation, as well as reduced interleukin (IL)-4 and immunoglobulin-E (IgE) levels in bronchoalveolar lavage fluid could be observed after modeling with carrageenan (Wang, M. M. et al., 2022).