YAP1 and neoplasm: Comparing Yap1 mutation in human lineage (S340A in H0825 cells) to the murine lineage A204P in M0825 cells, P0825 cells, and P0825-generated PDX P0825-984L tumor, the mutations were sitting on different domains in Yap1, which obviously was not horizontally passed form human tumor to the murine stromal cells, but an independent mutation in the murine lineage (Table 3).