Curcumin, an antioxidant and anti-inflammatory agent, can reduce the expression of ROS and NO to suppress oxidative stress and inhibit the NF-κB pathway and the expression of TNF-α, IL-1, IL-6, and IL-8 in macrophages of mouse models; thus, it has a potential therapeutic effect on endometriosis (175). The gene discussed is IL1B; the disease is endometriosis.