An earlier study showed that immature dentate granule cells (DGCs) emit brain-derived neurotrophic factor (BDNF) and that glioblastoma stem cells (GSCs) express neurotrophic receptor kinase 2 (NTRK2), also known as TrkB, an appropriate receptor for BDNF (35). The gene discussed is BDNF; the disease is glioblastoma.