To test the hypothesis, we first examined the expression of TNFR2 in different types of tumor-infiltrating T cells, by re-analyzing and integrating the pan-cancer single-cell landscape with UMAP visualization from the Zemin Zhang group’s study (28), based on their framework of scDVA (short for single-cell RNA-seq data visualization and analysis) among those various tumor types. This evidence concerns the gene TNFRSF1B and cancer.