CELA1 and pulmonary emphysema: In the CS model, <i>Cela1</i> <sup><i>-/-</i></sup> <i>&AAT</i> <sup>-/-</sup> mice had worse emphysema than <i>AAT</i> <sup><i>-/-</i></sup> , and in the aging model, 72-75 week-old <i>Cela1</i> <sup><i>-/-</i></sup> <i>&AAT</i> <sup>-/-</sup> mice had less emphysema than <i>AAT</i> <sup>-/-</sup> mice.