Cluster 27, activated emTc, showed higher expression of CXCR3 (fold change GSD1b/control = 1.78, p-value = 0.01, Fig. 3A), which is considered to represent an activation marker for CD8+ T cells; for this effector memory T cell population, it likely indicates activation and targeting to sites of infection[16]. This evidence concerns the gene CXCR3 and infection.