APC and Familial adenomatous polyposis: Given the potential harms for ultrasound screening such as psychological issues, decreased quality of life, financial issues, and high false-positive rates due to its low specificity (55% [58]), we agree with the opinion of Chenbhanich and co-workers that FAP patients with high-risk factors for TC (such as a young female with an APC mutation proximal to the 5′ end) rather than every FAP patient should receive thyroid ultrasound screening [4].