However, the trend was reversed in colorectal cancer, where high ELF3 levels correlated with better patient prognosis in terms of overall survival, relapse-free survival and metastasis-free survival (GSE16125, GSE39582, GSE28814 and GSE28722) (Fig. 5B, S5D-F), similar to reports in ovarian [26] and bladder cancer [25]. Here, ELF3 is linked to urinary bladder cancer.