GDF15 and coronary artery disorder: There were no discernible differences between the two groups in terms of clinical results like alcohol consumption, smoking, etc. Participants with HUA who also suffered from CAD had higher levels of Urea, Cr, TG, TC, UA, LDL-c, NEFA and GDF-15 while HDL-c levels were lower, suggesting compromised renal function and dysfunctional lipid metabolism.