IL4 and neoplasm: Functional enrichment analysis of the DEGs between tumor and normal myeloid cells (Supplementary Fig. 1c) revealed that digestion- and metabolism-related functional modules were enriched in normal tissue, whereas genes up-regulated in tumor samples were significantly enriched for immune-associated terms, such as interferon signaling, interleukin 4 and interleukin 13 signalings, and toll-like receptor cascades (Supplementary Fig. 1d).