While JIMT-1 cells released into BO-264-containing media strongly arrested at mitosis as shown by sustained cyclin B1 expression and p-H3 levels (Fig. 2H), MCF-7 cells released into BO-264-containing media could still progress through mitosis (Supplementary Fig. S3F), demonstrating the key role of TACC3 in mitotic progression, potentially specific to cancer cells with CA. Here, CCNB1 is linked to cancer.