TACC3 and cancer: As shown in Fig. 1A, TACC3 is higher in breast cancer tumors with high CA20 score in the METABRIC dataset [23], and among high CA20-expressing patients, those who express higher TACC3 exhibit much worse survival as compared to those who express lower TACC3 (Fig. 1B), suggesting that TACC3 may be critical for the outcome of patients with CA.