The immunostaining tumor tissues of mammary and liver with Ki-67 (Fig. 5a–c) illustrated that CD NPs exhibited the highest suppressive potential on this proliferative marker, by 9.61 and 69.45-folds, respectively, compared to ZD NPs (3.00 and 1.92-folds, respectively) and Fu (2.73 and 1.71-folds, respectively). The gene discussed is MKI67; the disease is neoplasm.