Similar to the previous list of 57 RFX7 target genes [23] and in agreement with RFX7’s tumor suppressor function [1], we identified multiple tumor suppressors among the 33 novel targets, such as MAFTRR [33] (Fig. 3b), MIR22HG [34–36], and ARRDC3 [37, 38] (Fig. 3c). The gene discussed is MIR22HG; the disease is neoplasm.