Moreover, SERPINA3 and m6A levels in monocytes were negatively correlated with the clinical parameters of inflammation and myocardial dysfunction such as C-Reactive Protein (CRP) and Troponin T, High Sensitivity (hs-TnT) (Fig. 10i–l), indicating the protective functions of SERPINA3 and RNA methylation of blood monocytes in sepsis. The gene discussed is SERPINA3; the disease is Sepsis.