ABLIM2, CDKL5, RHOJ, and PDCD1 displayed hypermethylation, while ZNF267 showed hypomethylation in patients with osteoporosis.177 Whole blood analysis in individuals of Asian Indian origin was performed to analyse CpG methylation in the bone morphogenetic protein 2 (BMP2) promoter through bisulfite-specific polymerase chain reaction (PCR) on the genomic DNA (gDNA) samples. Here, BMP2 is linked to osteoporosis.