Kong et al.222 proved that BAF60a interacts with the transcription factor Atf3 to regulate adipose tissue macrophages (ATMs) inflammation activation and insulin resistance in WAT through chromatin remodelling–mediated epigenetic mechanisms.222 BAF60c, also called Smarcd3, is a transcriptional cofactor enriched in fast-twitch muscles. This evidence concerns the gene SMARCD3 and Insulin resistance.