After GSEA analysis, we found that POSTN-associated genes were involved in adaptive immune responses; NOX1-associated genes were involved in antigen processing and presentation; RNF182-associated genes were involved in viral infection and innate immunodeficiency; and, SYT4-associated genes were involved in the NOD-like receptor signaling pathway and TGF-β signaling pathway. The gene discussed is SYT4; the disease is viral infectious disease.