KRAS and colonic neoplasm: The correlations between KRAS mutations and clinicopathological characteristics in our study were consistent with other published studies showing that patients bearing KRAS mutations are associated with aggressive histological features such as advanced tumor status, poor differentiation, and distal metastasis.[16] KRAS mutation was associated with right-sided colon tumor (62.1%, P < .000), and hotspot mutation on codon 12 exon 2 was dominant, accounting for 75.1% of all KRAS alleles (Tables 2 and 3).