AKT1 and type 2 diabetes mellitus: oral taxon 299, P. bryantii, P. melaninogenica), Intestinibacter bartlettii, Anaerococcus prevotii, lipid metabolites (especially phospatidylcholines), hepatic function associated genes, lipid metabolism and cardiomyopathy pathways, subcutaneous adipose tissue IL6 and SELE genes involved in inflammatory and immune system pathways and mesenteric adipose tissue genes enriched in prolactin signaling, T2D and PI3K-Akt signaling pathways (S14 Fig).