To further assess miRNA‐483‐3p and NDRG1 role in CRC EMT and invasive growth, by a complementary experimental approach we exploited CRC729 and CRC254 m‐colospheres, previously derived from CRC729 and CRC254 PDX [7], which express constitutively high miRNA‐483‐3p levels (Fig. 1D). The gene discussed is NDRG1; the disease is colorectal carcinoma.