To address the role of CALHM6 in the immune system during infection, we focused on the intracellular pathogen Listeria monocytogenes (L. monocytogenes), a Gram‐positive bacterium that can cause serious infections in children, elderly, immunocompromised and pregnant people (Radoshevich & Cossart, 2018). Here, CALHM6 is linked to infection.