SCRIB and neoplasm: The JAK-STAT pathway is an inducer of cell growth and proliferation (Zoranovic et al., 2013); in Drosophila, its ligands are upregulated in scrib mutant cells (Bunker et al., 2015), it is required for scrib mutant cell proliferation (La Marca et al., 2021), it is upregulated in scrib mutant RasV12 tumours (Atkins et al., 2016) and it cooperates with Ras in tumour growth (Herranz et al., 2012; Wu et al., 2010).