BRCA1 and esophageal cancer: Male relatives of BRCA1 carriers had significantly higher risks of esophageal cancer (RR = 2.33, 95% CI 1= 0.36-4.00; P = 0.002) and lymphoma (RR = 4.77, 95% CI = 1.92-11.86; P = 0.005) than male relatives of non-carriers.