BRCA1 and prostate carcinoma: Similarly, we found a significantly increased risk for prostate cancer in male relatives of BRCA2 carriers (RR = 4.86; P = 0.001), but a non-significant risk in male relatives of BRCA1 carriers (RR = 2.19; P = 0.241); our finding is in agreement with previous studies3,7,9,11,17,18.