BRCA2 and prostate carcinoma: In contrast, male relatives of BRCA2 carriers had significantly higher risks of pancreatic (RR = 4.34, 95% CI = 2.17-8.68; P = 0.001) and prostate cancers (RR = 4.86, 95% CI = 2.20-10.75; P = 0.001) than male relatives of non-carriers.