LGALS12 and acute myeloid leukemia: We found LGALS12 expression in the bone marrow only is border line significantly associated with AML-M4 compared to the other AML subtypes (p-value = 0.05) (data not shown), however, our methylation analysis showed a statistically significant association between complete methylation and unmethylation in the mono subtype only (p-value = 0.01).