This is consistent with the PPI analysis wherein the expressions of ADLH3A1, GSTA1, GSTM1, and HPGDS were upregulated and those of CYP2C9, CYP2E1, and UGT1A6 were downregulated in the high-BMI CRC patient group with good prognosis. The gene discussed is CYP2E1; the disease is colorectal carcinoma.