Figure 5 visually illustrates examples of PD-L1+ immune cells localized to the stroma and DSI among proliferative leukoplakia and localized leukoplakia tissues, highlighting the significant increase in PD-L1+ immune cell abundance among high-risk proliferative leukoplakia cases when compared with localized leukoplakia utilizing MIF digital overlay. The gene discussed is MIF; the disease is Oral leukoplakia.