Several chemokines (CCL3, CCL4, CCL5, CCL3L1, CCL21, CCL26, CXCL8, CXCL9, CXCL10, CXCL12, and CXCL13) have been reported as risk factors for RA development (11–25). This evidence concerns the gene CCL3 and rheumatoid arthritis.