CCR6 promotes Th17 cell recruitment into the inflamed joint in SKG arthritic mice (155), myostatin-deficient (KO) mice, TNF-α transgenic (Tg) arthritic mice (156), and chemotactic ability of Th17 cells derived from patients with RA in vitro model (155, 157). The gene discussed is CCR6; the disease is rheumatoid arthritis.