ZDHHC22 and liver cancer: Based on LASSO logistic regression and SVM-RFE algorithms, we identified GNG8, MYH1, CHRNA3, DPEP1, PRSS35, CKMT1B, CNKSR1, C14orf180, POU3F1, SAG, POU2AF1, IGFBPL1, CDCA7, ZNF492, ZDHHC22, and SFRP2 as DEGs of liver cancer immunotherapy.