CD4 and chronic kidney disease: Intriguingly, the expression level of ICAM1 was positively correlated with neutrophils, Mφ0, Mφ1, CD4+ T memory cells, activated mast cells, gamma delta (γδ) T cells, and eosinophils, while negatively linked with regulatory T cells, naive B cells, plasma cells, resting NK cells and resting mast cells in both CKD and UC (Figures 7A, B).