CRP and depressive disorder: First, the normal distribution tests demonstrated that the values of skewness and kurtosis for depression across 2011, 2013, and 2015 ranged from 0.84 to 0.97 and from 0.17 to 0.79, respectively; the values of skewness and kurtosis for CRP across 2011 and 2015 ranged from 1.96 to 2.34 and from 4.29 to 6.25, respectively (detailed information in Supplementary Table S1).