CD8A and neoplasm: In contrast to KPC3 tumors, αTGF-β administration significantly increased the Reo-induced influx of total T cells in MC38 tumors (Fig. 3H), as well as the frequency of reovirus-specific (μ1133–140 Tm+) and tumor-specific (Rpl18 Tm+) CD8+ T cells compared with the group that received Reo only (Fig. 3I).