IDH3A and mesenchymal cell neoplasm: One high-proliferative cluster characterized by high EMT signature consisted of mesenchymal tumors, including the sarcomas, mesenchymal subtype of OV, and isocitrate dehydrogenase (IDH) wild-type glioblastoma multiforme, of which more than one-third were previously reported to show a mesenchymal phenotype (ref. 46; Fig. 1E).