ATP5B, COX5A, GAPDH NDUFV2, SOD1, UQCRC1, and UQCRC2 have been reported as sleep deprivation and sleep disorder-related genes, and these studies have contributed to the development of candidate biomarkers for the diagnosis and treatment of plateau-induced sleep disorders (Abdo Qaid et al., 2021; Chen et al., 2021). The gene discussed is COX5A; the disease is sleep disorder.