Previous reports provided evidence about the role of MMP-1 and MMP-8, also known as collagenase 1 and collagenase 2, respectively, in the development of idiopathic pulmonary fibrosis [36], ischemic stroke, small vessel stroke [37], acute hepatitis [38], and various cancer types [39]. Here, MMP8 is linked to idiopathic pulmonary fibrosis.