7. Adequate bone marrow, liver and renal function assessed within 14 days before starting study treatment as defined by the following parameters:Bone marrow:Absolute Neutrophil Count (ANC) ≥ 1.5 x 109/LHemoglobin (Hgb) ≥ 9 g/dLPlatelets ≥ 100 x 109/LLiver function:Serum total bilirubin ≤ 1.5 x upper limit of normal (ULN) Aspartate aminotransferase (AST) (serum glutamic oxaloacetic transaminase [SGOT]) and ALT (SGPT) ≤ 2.5 x ULN, except in patients with tumor involvement of the liver who must have AST and ALT ≤ 5 x ULNRenal function:Serum creatinine ≤ 1.5 x ULN or 24-hour clearance ≥ 50 mL/min. This evidence concerns the gene GOT1 and neoplasm.