CRY1 and fragile X syndrome: Additionally, clock genes period1 (PER1) and cryptochrome1 (CRY1) were disrupted in a mouse model of Fragile X Syndrome (FXS), which is one of the most known genetic causes of autism (Lewis et al. 2007; Zhang et al. 2008; Spencer et al. 2011; Dolan et al. 2013; Sare et al. 2017).