Among these genes, metallopeptidases (ADAM10, MMP2, MMP9), inflammatory (IL6, IL6R, IKBKB, MIF), cell cycle and proliferation (CDKN2D, MYC) or apoptotic (BCL2) genes have their important position suggesting the role of this miRNA in fibrotic processes during CKD development. Here, IL6R is linked to chronic kidney disease.