Among these genes, metallopeptidases (ADAM10, MMP2, MMP9), inflammatory (IL6, IL6R, IKBKB, MIF), cell cycle and proliferation (CDKN2D, MYC) or apoptotic (BCL2) genes have their important position suggesting the role of this miRNA in fibrotic processes during CKD development. The gene discussed is BCL2; the disease is chronic kidney disease.