Peng et al. illustrated that METTL14 facilitates LPS-induced PD-L1 expression in HCC cells, METTL14 upregulation by LPS strengthens the stability of MIR155HG and further regulates the levels of PD-L1 via the miR-223/STAT1 axis [131]. This evidence concerns the gene CD274 and hepatocellular carcinoma.