Within this group, we identified K08D12.3, an ortholog of the human ZNF9, which is mutated in myotonic dystrophy type 2, mbl-1, a MUSCLEBLIND-type of mRNA splicing regulator required for muscle dense body organization, locomotion, and vulval morphogenesis, and etr-1, an ortholog of the human CUG-binding protein CUGBP1, which is required for embryonic muscle development and has been implicated in myotonic dystrophy (Supplemental Table S1). The gene discussed is CELF1; the disease is myotonic dystrophy type 2.