Furthermore, the results of RT-qPCR (Fig. 7E) presented that BMP7 expression levels were increased in NP tissues of STZ-induced T1DM rats injected with oe-BMP7, while there were no significant differences in regard to BMP7 expression levels in NP tissues of STZ-induced T1DM rats injected with oe-BMP7 and 4’MR. This evidence concerns the gene BMP7 and type 1 diabetes mellitus.